Invited Review Paper FUNCTIONALLY BIOPOLYMER SYSTEMS
نویسنده
چکیده
Advances in functionally biopolymer systems have provided new opportunities on basic science studies and bioengineering applications. In this review, the recent data on interaction mechanisms of synthetic polyelectrolytes with proteins and physico-chemical criteria for the construction of functionally biopolymer systems are reviewed. Also, the structure and structural-chemical features of protein-polyelectrolyte complexes are discussed. A special chapter is dedicated to metal-induced polycomplexes and described the peculiarity of phase transition in these systems. Complexes of proteins with polyelectrolytes may be considered as models for specific nucleoprotein complexes and nucleotide-protein complexation research. Such reactions may simulate the antigen-antibody interactions, the processes of assembling of viruses, chromatin, ribosome strains and other cell components in complicated biological systems. Applications of functionally biopolymer systems in immunology (polymeric immunogens for vaccine innovation) and radiobiology (active radioprotectors development) are discussed.
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